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Time to Focus: 5 Gastrointestinal Diseases You Should Know

  • Apr 15, 2025

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Gastrointestinal & Liver Center (Gastro-Intestinal & Scope Center)
The gastrointestinal (GI) system, a vital part of the body, is responsible for digestion, absorption, and excretion. It includes the mouth, pharynx, stomach, intestines, liver, gallbladder, and pancreas. Below are five common GI diseases:


1. Peptic Ulcer Disease

Symptoms:

  • Burning or gnawing pain in the epigastrium (upper abdomen), below the sternum, or left rib cage.

  • Pain worsens when hungry or after eating; relieved temporarily by food.

  • Severe cases: Vomiting blood, black stools, weight loss, loss of appetite.

Causes:

  • Helicobacter pylori infection (spread via contaminated food/water).

  • Long-term use of NSAIDs (e.g., aspirin, painkillers), certain acne medications.

  • Smoking, alcohol, stress, irregular meals, spicy foods.

Warning Signs Requiring Immediate Care:

  • Black or bloody stools.

  • Jaundice (yellowing skin/eyes).

  • Severe, prolonged abdominal pain.

  • Vomiting blood or persistent vomiting.

  • Difficulty swallowing.

  • Family history of GI diseases or palpable abdominal lumps.

Self-Care for Mild Cases (<2 weeks):

  • Take antacids.

  • Avoid smoking, alcohol, spicy foods.

  • Eat regular meals.

  • Exercise.

  • Limit NSAIDs.

When to Seek Medical Help:
If symptoms persist >1 month or worsen, endoscopy is required to check for ulcers, tumors, or cancer.


2. Gastroesophageal Reflux Disease (GERD)

Symptoms:

  • Heartburn (burning chest/upper abdomen pain).

  • Sour/bitter taste in the mouth, chronic sore throat.

  • Difficulty swallowing, lump-in-throat sensation.

  • Chronic cough, hoarseness, nighttime choking.

  • Asthma exacerbation, recurrent pneumonia.

Risk Factors:

  • Obesity, smoking, alcohol.

  • High-fat/spicy/acidic foods (e.g., chocolate, coffee, soda, fried foods).

  • Overeating, stress.


3. Ulcerative Colitis

Note: The original Thai text incorrectly discusses hepatitis B here. Translated as per source:
Hepatitis B spreads from mother to child during birth, especially if the mother is unaware of her infection. Early childhood infection often becomes chronic. Transmission routes include:

  • Unprotected sex, shared needles, unsterile medical procedures.

  • Blood transfusions, dialysis, organ transplants.

  • Household exposure to contaminated items (razors, nail clippers).

Symptoms:

  • Mild fever, nausea, vomiting, fatigue, jaundice.

  • Advanced stages: Liver lumps (often indicating late-stage disease).

Prevention:

  • Avoid alcohol, chemicals, toxins.

  • Maintain a healthy weight, exercise, and rest.

  • Fibroscan: A 5-minute ultrasound to detect liver fibrosis/cirrhosis, especially in heavy drinkers.

Chronic Hepatitis B Management:
Focuses on reducing liver inflammation to prevent cirrhosis and liver cancer.


4. Irritable Bowel Syndrome (IBS)

Symptoms:

  • Abdominal pain/cramps relieved by defecation.

  • Alternating diarrhea and constipation.

  • Bloating, gas, mucus in stools.

Diagnosis & Treatment:

  • Mild cases: Reassurance and lifestyle changes.

  • Severe cases: Medications to regulate bowel movements.


5. Gallstones

Overview:

  • Hard deposits (cholesterol/bilirubin) in the gallbladder.

  • Common in adults >40, especially women.

Symptoms:

  • Severe right upper abdominal pain (15 mins–hours), radiating to the right shoulder.

  • Nausea, vomiting, bloating, indigestion.

  • Acute cholecystitis: Fever, jaundice, dark urine.

Asymptomatic Cases:
Often discovered during routine check-ups.

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